Everolimus

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Everolimus-eluting coronary stents

Bare metal stents enabled a reduction in the risk of early procedural complications and restenosis in comparison with balloon angioplasty alone, but introduced a new and device-specific iatrogenic condition, ie, in-stent restenosis due to increased neointimal hyperplasia. Sirolimus- and paclitaxel-eluting stents reduce restenosis and the need for new revascularizations in comparison with bare m...

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Comparison of Everolimus- and Biolimus-Eluting Coronary Stents With€Everolimus-Eluting Bioresorbable Vascular Scaffolds

Fro ini Du an res da Bio (CR Lis Yo Ma BACKGROUND The first CE-approved bioresorbable vascular scaffold (BVS) is effective at treating simple lesions and stable coronary artery disease, but it has yet to be assessed versus the best-in-class drug-eluting stents (DES). OBJECTIVES This study sought to compare the performance of a BVS with that of everolimus-eluting stents (EES) and biolimus-elutin...

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Lenvatinib/everolimus improves survival better than everolimus alone in metastatic renal cell cancer.

Progression-free survival (PFS) was longer with a combination of lenvatinib (Lenvima, Eisai) and everolimus (Afinitor, Novartis) than with everolimus alone as second-line treatment for metastatic renal cell cancer (RCC), according to the results of a phase 2 trial. Dr Robert Motzer, a professor of medicine at Weill Cornell Medical College in New York, New York, presented results from the study ...

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Long-Term Efficacy and Safety of Everolimus-Eluting Bioresorbable Vascular Scaffolds Versus Everolimus-Eluting Metallic Stents

Second-generation metallic drug-eluting stents (DES) have been widely recommended for percutaneous coronary intervention. One of the main drawbacks of these devices is the risk of late adverse events (ie, beyond 1 year), particularly repeat revascularization, which are partly related to the persistence of the metallic stents in the coronary artery wall. In this context, the bioresorbable vascul...

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Mechanical properties of the everolimus-eluting bioresorbable vascular scaffold compared to the metallic everolimus-eluting stent

BACKGROUND Everolimus-eluting bioresorbable vascular scaffolds (BVS) represent an innovative treatment option for coronary artery disease. Clinical and angiographic results seem promising, however, data on its immediate procedural performance are still scarce. The aim of our study was to assess the mechanical properties of BVS by Optical Coherence Tomography (OCT) in clinical routine. METHODS...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2016

ISSN: 0923-7534

DOI: 10.1093/annonc/mdw484.002